< Variants

How does a variant of the SARS-CoV-2 coronavirus spread?

Text updated on 2021-01-14

Some variants of the coronavirus are disappearing while others are spreading in human populations. A given variant can spread through a windfall effect (the variant was present at the right time in the right person - from the point of view of the virus) or through natural selection if it spreads better than the other variants.

There are two possible reasons for the spread of a variant: chance and natural selection.

A variant that arrives first in a host population starts the race ahead and benefits from what is called a "founder effect". In the case of SARS-CoV-2, risky host behaviors or social habits unrelated to the viral mutation may cause superpropagation episodes (See question What is a super-propagating situation for the COVID-19 ?). A mutation may occur by chance in these individuals involved in superpropagation episodes, or it may be transmitted to a large number of people by a "windfall effect". These exceptional transmission events can lead to a dramatic increase in the frequency of certain variants without necessarily being due to an adaptation of the virus. Indeed, with the exponential growth of the virus, a slightly more frequent mutation may become the majority within a few weeks or months.

Natural selection is another mechanism that can lead to the propagation of a variant. Mutations appear randomly and three effects are possible: some will be neutral (no effect on the coronavirus), some harmful to the coronavirus (mutation that decreases its transmissibility) and some beneficial (mutation that increases its transmissibility). In the case of a mutation that is beneficial for the coronavirus, the variant will have an advantage over the initial form, it will spread more rapidly to a larger number of people and, thus, become more common in the population.

facebook twitter linkedin


A book for the general public that explains the general principles of evolution and gives beautiful examples of evolution.

Coyne, J. A. (2010). Why evolution is true. Oxford University Press.

Further reading

What is a mutation for the SARS-CoV-2 coronavirus?

What is a variant of the SARS-CoV-2 coronavirus?

Which variants of the SARS-CoV-2 coronavirus have attracted attention?

What do we know about the British variant?

Do the variants call into question the efficacy of the vaccines?